Rituxan (Rituximab) Infusion Cost in 2026, and How to Lower It
A single Rituxan (rituximab) infusion is commonly billed at $5,000 to $13,000 or more, with a hospital outpatient department at the high end and a doctor’s office or standalone infusion center much less for the exact same drug and dose. The two biggest levers are where you get infused and switching to a biosimilar, and if you qualify, the maker can provide the drug free.
- Site of care is a major driver. The same rituximab infusion is often billed 2 to 3 times more at a hospital outpatient department than at a physician office or a freestanding infusion center.
- Rituximab biosimilars (Truxima, Ruxience, Riabni) are the same class of medicine at a lower price. Whether one is right for you is a decision for you and your prescriber.
- If you are uninsured or underinsured, the Genentech Patient Foundation (1-888-941-3331) can provide Rituxan free to patients who qualify under an income limit, and ships it to your infusion center. On Medicare, use a charity copay fund instead.
What a Rituxan Infusion Costs
Rituximab is dosed by the condition and, in cancer, by body surface area (rheumatoid arthritis is usually 1,000 mg given twice, two weeks apart), and it is billed under J-code J9312, so the drug portion scales with your dose. These are national estimates; your bill depends on dose, site, and plan.
| Where you get it | Typical billed cost per infusion |
|---|---|
| Hospital outpatient department | ~$9,000 to $18,000+ |
| Doctor’s office / infusion center | ~$5,000 to $11,000 |
| Biosimilar (Truxima, Ruxience, Riabni) | ~10 to 30% less |
| With manufacturer free-drug program | as low as $0 (drug) |
Rituximab is given as a course of infusions, and the number and size of doses depends on your condition, so the total cost adds up quickly, which is why the site and biosimilar levers matter so much.
Already got a bill for your Rituxan (rituximab) infusion? Check if you were overcharged.
A typical Rituxan (rituximab) infusion runs $5,000 to $13,000 without insurance. Enter what you were charged and we will flag it.
Or send us the bill and we will fight it down. 64% of cases reduced.
How to Lower the Cost
Ask to move the infusion to a lower-cost site
If your treatment plan allows, ask your prescriber whether your infusions can move from a hospital to an in-network doctor’s office or a freestanding infusion center. This is usually a large saving, for both you and your plan, and does not change the medicine.
Ask about a rituximab biosimilar
Truxima (rituximab-abbs), Ruxience (rituximab-pvvr), and Riabni (rituximab-arrx) are FDA-approved biosimilars to Rituxan. Many plans prefer them and they cost less. Whether to switch is a decision for you and your prescriber, but it is worth raising.
Use the right assistance for your situation
Uninsured or underinsured? The Genentech Patient Foundation (1-888-941-3331) may provide Rituxan free under an income limit (generally up to 500% of the federal poverty level), ships it to your infusion center, and does not require citizenship information. Commercially insured? A Genentech copay card can cut your coinsurance. On Medicare? Use a charity fund like the PAN or HealthWell Foundation. Our help paying for medication tool and our guide to patient assistance programs point you to the right one.
Check the bill for errors, especially the J-code units
Because rituximab is dosed by the milligram and billed under J9312, a units or facility-fee error can multiply the charge. CareRoute Bill Defense checks the units, drug wastage, facility fees, and network status, and disputes errors, with no fee unless we save you money.
Frequently Asked Questions
How much does a Rituxan infusion cost?
A single rituximab infusion is commonly billed at about $5,000 to $13,000 or more, and can run higher at a hospital because of the facility fee. The drug is dosed by your condition and, in cancer, by body surface area, so your exact cost depends on your dose, site, and plan.
Why is my infusion so much more expensive at the hospital?
Hospitals add a facility fee and negotiate higher drug rates, so the identical rituximab infusion is routinely billed 2 to 3 times more in a hospital outpatient department than in a physician office or an infusion center. If your treatment plan allows, ask your prescriber whether the infusion can move to a lower-cost site.
Is a biosimilar as good as Rituxan, and is it cheaper?
Rituximab biosimilars (Truxima, Ruxience, Riabni) are FDA-approved as highly similar to Rituxan with no clinically meaningful differences, and they generally cost less. Whether to use one is a decision between you and your prescriber, and many plans prefer them.
Can I get Rituxan for free?
If you are uninsured or underinsured and your income is under the program limit (generally up to 500% of the federal poverty level), the Genentech Patient Foundation (1-888-941-3331) can provide Rituxan at no cost and ships it to your infusion center. It does not require citizenship information. Commercially insured patients can use a Genentech copay card, and Medicare patients can use independent charity funds.
Will my insurance out-of-pocket maximum cap what I pay?
For in-network, covered care, yes. Once you hit your plan’s out-of-pocket maximum, it covers 100% of remaining in-network covered costs for the year. But an out-of-network site or provider can bill amounts that do not count toward that cap, which is why confirming network status of every party matters.
Related
Sources
- CMS Average Sales Price (ASP) drug pricing files (J9312 rituximab and biosimilar J-codes)
- FDA (rituximab biosimilar approvals: Truxima, Ruxience, Riabni)
- Health Care Cost Institute and AHA (hospital facility fees and site-of-care differentials)
- Genentech Patient Foundation (eligibility and free-drug program, 1-888-941-3331)
Prices are national estimates for 2026 and vary widely by dose, site, and plan. Any change of drug or infusion site is a decision for you and your prescriber. This page is educational and is not medical or financial advice. Last updated August 2026.