Help Paying for an Infusion or Specialty Drug
The drug makers behind the most expensive infusions run foundations that give the medicine away free to patients who qualify, and where you get the infusion can change the bill two to three times over. Answer a few questions and we will point you to the right lever for your situation.
Find the cheapest way to get your drug
A few questions, nothing saved. This is a guide, not an official decision, and your prescriber signs off on any change.
2. Your insurance situation
The four ways to lower an expensive drug bill
Manufacturer coupons are only one lever, and often not the biggest. Which one fits you depends mostly on your insurance and income.
Manufacturer free-drug foundation
Best for: Uninsured, or insured but the plan will not cover the drug
The maker gives the medicine free, under an income limit (often up to 400% to 500% FPL). Your prescriber submits the form; the drug ships to your infusion center.
Independent charity foundation
Best for: Insured, especially Medicare (who cannot use copay cards)
Nonprofits (PAN, HealthWell, Good Days, PAF) cover your coinsurance through disease-specific funds. Funds open and close, so check often.
Manufacturer copay card
Best for: Commercial or employer plan that covers the drug
Pays your coinsurance down toward $0, up to an annual max. Watch for the copay accumulator, where the dollars do not count toward your deductible.
Lower-cost site of care
Best for: Anyone getting an infusion
The same infusion is often billed 2-3x more at a hospital than at a standalone center, a doctor’s office, or home. Ask your prescriber to move it.
Free-drug foundations for common infusions
If you are uninsured, or your plan will not cover the drug, these manufacturer foundations can provide it at no cost under an income limit. Your doctor’s office submits the request. Income caps update and hardship is often reviewed higher, so apply even if you think you are a little over.
| Drug | Maker foundation | Income cap | Phone |
|---|---|---|---|
| Ocrevus (ocrelizumab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Rituxan (rituximab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Actemra (tocilizumab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Herceptin (trastuzumab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Avastin (bevacizumab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Tecentriq (atezolizumab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Xolair (omalizumab) | Genentech Patient Foundation | up to 500% FPL | (888) 941-3331 |
| Remicade (infliximab) | Johnson & Johnson Patient Assistance Foundation | up to 500% FPL | 1-800-652-6227 |
| Stelara (ustekinumab) | Johnson & Johnson Patient Assistance Foundation | up to 500% FPL | 1-800-652-6227 |
| Simponi Aria (golimumab) | Johnson & Johnson Patient Assistance Foundation | up to 500% FPL | 1-800-652-6227 |
| Darzalex (daratumumab) | Johnson & Johnson Patient Assistance Foundation | up to 500% FPL | 1-800-652-6227 |
| Keytruda (pembrolizumab) | Merck Patient Assistance Program | up to 400% FPL | 1-800-727-5400 |
| Opdivo (nivolumab) | BMS Patient Assistance Foundation | up to 300% FPL | 1-800-861-0048 |
Not listed here? Nearly every maker runs one. See our full guide to patient assistance programs for more drugs and programs.
On Medicare? Use a charity foundation
Medicare patients cannot use manufacturer copay cards, but these independent nonprofits cover coinsurance through disease funds. Funds open and close, so check a few:
Site of care is the biggest lever
The same infusion, same drug, same dose, is routinely billed two to three times higher at a hospital outpatient department than at a standalone infusion center, a physician’s office, or home infusion. If you are stable, ask your prescriber whether it can move. More on infusion costs.
How the free-drug path works
- Your prescriber applies, not the pharmacy. The doctor’s office completes a prescriber form; you sign a patient consent form. Ask them to start it.
- The drug ships to your infusion site. Once approved, the maker sends the medicine to your doctor or infusion center for your treatments, so you never pay for the drug itself.
- Income limits are generous and forgiving. Many programs reach 400% to 500% of the poverty level and review hardship above that. Limits also scale with household size, so check your real size before assuming you are over.
- Citizenship is usually not required. Programs generally ask about U.S. residency, not citizenship. The Genentech Patient Foundation, for example, does not collect citizenship information.
Already got a bill for an infusion or drug?
Infusion and specialty-drug bills are among the highest-value bills to challenge, a facility overcharge, a coding error, or a balance you should not owe once assistance is applied. Send it to us. We review and negotiate it. Free to submit, you only pay if we save you money.
Send us the billFree to submit. You only pay if we save you money.
Frequently asked questions
Can the drug manufacturer really give me an infusion drug for free?
Yes. Most makers of expensive infused and specialty drugs run a Patient Foundation (a patient assistance program, or PAP) that provides the medicine at no cost to patients who are uninsured, or whose insurance will not cover that specific drug, and who fall under an income limit (commonly up to 400% to 500% of the federal poverty level, with hardship reviewed higher). Your prescriber’s office submits the request, and once approved the drug is shipped to your doctor or infusion center for your treatments. For example, the Genentech Patient Foundation gives Genentech medicines free to eligible patients and does not require citizenship information. You apply through your doctor, not the pharmacy.
What is the difference between a free-drug foundation and a copay card?
They help different people. A manufacturer FOUNDATION (PAP) gives the actual drug free and is meant for uninsured or underinsured patients under an income limit. A manufacturer COPAY CARD is for people with commercial or employer insurance that already covers the drug; it pays down your coinsurance or copay, often to close to $0, up to an annual maximum. Copay cards cannot be used by people on Medicare or Medicaid because of federal rules. Medicare patients use independent charity foundations (like the PAN or HealthWell Foundation) for that same help instead.
Why does the same infusion cost so much more at a hospital?
Site of care is the single biggest cost lever for an infused drug. The identical drug and dose are often billed two to three times higher at a hospital outpatient department than at a standalone infusion center, a doctor’s office, or through home infusion, because hospitals add a large facility markup on top of the drug. If you are stable, ask your prescriber whether your infusion can be moved to a lower-cost site. It can cut both your share and your plan’s cost substantially, without changing the medicine.
I have Medicare. What are my options for an expensive drug?
Manufacturer copay cards are off-limits on Medicare, but you have other levers. Independent charity foundations (PAN Foundation, HealthWell, Good Days, Patient Advocate Foundation) run disease-specific funds that cover coinsurance for Medicare patients when a fund is open. Medicare Extra Help (the Part D Low-Income Subsidy) lowers Part D drug costs if your income qualifies. And for Part B infused drugs, site of care still applies. If your income is limited, also check whether you qualify for help paying for Medicare.
Does this cost me anything, and what does CareRoute do?
Applying to any of these programs is free, and this tool is free. CareRoute earns money only on Bill Defense, where we review and negotiate a medical bill you already have, and only if we save you money. An infusion or specialty-drug bill is one of the highest-value bills to send us, whether it is a facility overcharge, a coding error, or a balance you should not owe once assistance is applied.
Related
Sources & references
A general note: income limits, open funds, and program details change, and your prescriber decides on any drug substitution or change in where you are treated. This is general information to point you to the right program, not medical or financial advice or an official eligibility decision. Confirm details with the program or your infusion center. Last updated: August 2026.