IVIG Infusion Cost in 2026, and How to Lower It
IVIG (intravenous immune globulin) is dosed by body weight and priced by the gram, so a single treatment is commonly billed $5,000 to $15,000 or more, and a high-dose course can run much higher. The biggest levers are where you infuse (hospital versus home), and for many patients, switching to subcutaneous (SCIG) home therapy.
- IVIG is priced per gram (roughly $100 to $350/gram billed) and dosed by weight, so a 1 to 2 g/kg course for an average adult can total tens of thousands of dollars.
- Site of care is the biggest lever. A hospital outpatient department adds a large facility fee; a doctor’s office, ambulatory infusion suite, or home infusion is usually far cheaper for the same product.
- For many conditions, subcutaneous immune globulin (SCIG) done at home can lower total cost and avoid facility fees. Ask your prescriber if it is an option for you.
What IVIG Costs
IVIG comes in several brands (Gammagard, Privigen, Gamunex-C, Octagam, Flebogamma and others), each with its own J-code and price. Your dose is based on your weight, so the drug portion scales with you. These are national estimates.
| Where you get it | Typical billed cost per treatment |
|---|---|
| Hospital outpatient department | ~$10,000 to $30,000+ |
| Infusion center / home infusion | ~$5,000 to $15,000 |
| Subcutaneous (SCIG) at home | often lower total |
| With manufacturer or foundation help | as low as $0 (drug) |
Many patients need IVIG on a repeating schedule (every 3 to 4 weeks), so annual cost is very high, which is why the site-of-care and SCIG levers matter so much.
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How to Lower the Cost
Move off the hospital outpatient department
Ask your prescriber and plan whether your IVIG can be given at a freestanding infusion center or through home infusion instead of a hospital. The drug is the same; you avoid the facility fee. This is usually the biggest single saving.
Ask whether subcutaneous (SCIG) is an option
For several conditions, immune globulin can be given under the skin at home instead of by IV. For eligible patients this can lower total cost and remove facility fees. Whether it fits your condition is a decision for your prescriber.
Use the right assistance for your situation
IVIG makers (Takeda, Grifols, CSL Behring, Octapharma and others) run patient assistance and copay programs, and independent charity funds help insured and Medicare patients with coinsurance. Our help paying for medication tool points you to the right program for your brand, insurance, and income.
Have the bill checked, grams and units especially
IVIG is billed per gram, so a units or wastage error can add thousands. CareRoute Bill Defense checks the grams billed against your dose, the facility fees, and network status, and disputes errors, with no fee unless we save you money.
Frequently Asked Questions
How much does IVIG cost per treatment?
IVIG is priced by the gram (roughly $100 to $350/gram billed) and dosed by weight, so a single treatment is commonly billed $5,000 to $15,000, and a high-dose course at a hospital can exceed $30,000. Your exact cost depends on your weight, dose, brand, and where you infuse.
Why is IVIG so expensive?
Immune globulin is made from pooled human plasma, which is costly to collect and manufacture, and it is dosed by body weight so the volume needed is large. On top of the drug, a hospital adds a facility fee. That combination is why the same treatment can vary by tens of thousands of dollars depending on the site.
Is home infusion or subcutaneous IG cheaper?
Often, yes. Home infusion avoids the hospital facility fee, and for eligible patients subcutaneous immune globulin (SCIG) self-administered at home can lower total cost further. Whether either fits your condition is a decision for your prescriber, but both are worth asking about.
Is there financial help for IVIG?
Yes. IVIG makers run patient assistance and copay programs, and independent nonprofits (PAN Foundation, HealthWell, Good Days) run disease-specific funds that cover coinsurance, including for Medicare patients who cannot use manufacturer copay cards. Which one fits depends on your brand, insurance, and income.
Will my out-of-pocket maximum cap the cost?
For in-network, covered care, yes: once you reach your plan’s out-of-pocket maximum, it pays 100% of remaining in-network covered costs for the year. Out-of-network sites or providers can bill amounts that do not count toward that cap, so confirm the network status of the infusion site, the physician, and any home-infusion pharmacy.
Related
Sources
- CMS Average Sales Price (ASP) drug pricing files (IVIG brand J-codes)
- Health Care Cost Institute and AHA (hospital facility fees and site-of-care differentials)
- Immune Deficiency Foundation and manufacturer resources (IVIG vs SCIG, home infusion)
- PAN Foundation and HealthWell Foundation (disease-specific copay funds)
Prices are national estimates for 2026 and vary widely by weight, dose, brand, site, and plan. Any change of therapy or infusion site is a decision for you and your prescriber. This page is educational and is not medical or financial advice. Last updated August 2026.